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Symbol
Name
ID

Sptb
spectrin beta, erythrocytic
MGI:98387

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes

Increased mean corpuscular hemoglobin concentration

Reticulocytosis

Anemia

Hemolytic anemia

Spontaneous hemolytic crises

Acanthocytosis

Spherocytosis

Increased red cell osmotic fragility

Hypofibrinogenemia

Hypercoagulability

Extramedullary hematopoiesis

Splenomegaly

Disease(s) Associated with SPTB

hereditary spherocytosis

hereditary spherocytosis type 2

Mouse Phenotypes

enlarged spleen

extramedullary hematopoiesis

anemia

hemolytic anemia

abnormal erythrocyte morphology

decreased erythrocyte cell number

low mean erythrocyte cell number

increased erythrocyte cell number

decreased hematocrit

decreased cellular hemoglobin content

decreased hemoglobin content

decreased mean corpuscular hemoglobin

decreased mean corpuscular volume

increased nucleated erythrocyte cell number

anisocytosis

acanthocytosis

anisopoikilocytosis

increased erythrocyte protoporphyrin level

microcytosis

poikilocytosis

schistocytosis

spherocytosis

reticulocytosis

abnormal reticulocyte morphology

increased spleen red pulp amount

abnormal erythrocyte physiology

increased erythrocyte clearance

hemolysis

abnormal erythrocyte osmotic lysis

increased erythrocyte osmotic fragility

Availability

Mouse Genotype

Sptb^ja/Sptb^ja

Sptb^m1Jus/Sptb^m1Jus

Sptb^em1(IMPC)J/Sptb⁺

Sptb^ja/Sptb⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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